Nicotine Addiction: Fact or Fiction?

This week is National Stop Smoking Week.   I have worked with many smokers and have some views on smoking that may be useful for those of you who currently smoke and would like to quit.  To this end, I will blog several times this week in order to give you information that you will find useful.

Addiction is defined by compulsive drug-seeking and abuse, even in the face of Healthy lung shape world design logo concept idea with love heart shape symbolic sign of women human hands on blur green natural clean air greenery background: Element of this image furnished by NASAnegative health consequences.  Smokers would definitely fall under this category – but what are they actually addicted to, and how are they addicted?  Smoking addiction is in a class by itself, in my opinion.  Smokers assume that they use tobacco products on a regular basis because they are addicted to nicotine.  The truth, however, is that they are not physically addicted to the effects of nicotine. They are addicted to the psychological effects of nicotine.  I first became aware of this fact when a woman who routinely smoked at least 2 packs a day got pregnant.  She immediately stopped smoking for the entire pregnancy with no cravings and no side-effects from stopping.  How is this possible?  If she had been addicted to heroin instead, it would have been virtually impossible without severe physical withdrawal symptoms.

Research indicates that nicotine acts on the brain’s reward pathways – and those involving the neurotransmitter dopamine.  Nicotine increases dopamine in the “reward” circuits.  All the effects that smokers attribute to nicotine are actually the result of dopamine stimulation in the brain.  Nicotine is rapidly distributed to the brain with peak levels occurring within 10 seconds of inhalation.

Nicotine is also rapidly eliminated from the body, so the nicotine-stimulating effect on dopamine is short.  In order to maintain the drug’s effects, the smoker has to take another nicotine “hit”.

The problem with smokers is that they are usually dopamine deficient to begin with – and nicotine makes them feel “good”. The unfortunate thing about most current treatments for nicotine addiction is that they concentrate on the supposed physical Cigarette stub with smokeeffects of nicotine withdrawal.  Take the patch, for example.  The patch is designed to give decreasing nicotine doses over time assuming that this will allow a smoker to “wean off” nicotine.  The problem with this approach is that it doesn’t give the smoker more dopamine I.e., it doesn’t address the dopamine deficiency.  A chronic smoker will actually experience symptoms relating to “not enough” dopamine  (irritability, craving, depression, anxiety, cognitive and attention deficits, sleep disturbances) rather than nicotine “withdrawal” symptoms. In order to quit smoking, the dopamine deficiency must be addressed.  If we can get the smoker’s brain to make more dopamine or find another way to stimulate dopamine release, then

Stopping smoking can become relatively easy – and I have never met a smoker who really didn’t want to quit.

Until the next installment…

Dr. Gatis

Use It Or Lose It

No.  I am not talking about sex (although this may be true).  Brain cells need stimulation in order to “stay sharp”.  Regular brain exercise is as necessary as regular general bodily exercise.  Research from Rush Alzheimer’s Disease Center, published in the Journal of the American Medical Association looked at 800 older Americans over 4.5 years.  The individuals who challenged their brains several times per week had a 33% lower risk of Alzheimer’s than people who participated in brain-stimulating activities just several times a month.  Although I didn’t see bingo on the list, other activities included reading, doing puzzles, playing cards, doing crosswords and visiting museums.  Use them (brain cells) or lose them – does apply here.

Until next time…

Dr. Gatis

Marriage Does Have Its Advantages

Marriage can be a tax break – and most of us have made a joke about marriage “breaking” us.  Research shows, however, that healthy, unmarried people who rated their health as “excellent” were, on average, 75 percent more likely to die during the 20 year period studied than married people.  The benefits declined, however, as people’s health or marriage declined.  Unmarried people in “fair” health were only 40 percent more likely to Dollarphotoclub_70805976die than married people.

The American Psychological Association found that couples who later divorced had 34 percent higher levels of norepinephrine in their blood.  Norepinephrine is a stress hormone – and the implication is, of course, that being married is less stressful, or not being married is more stressful.  Professor Janet Kiecolt-Glaser, from the Institute for Behavioral Medicine Research at Ohio State University states that “marital quality is a good predictor of subsequent health” and how personal relationships, especially marriage, can translate into positive health outcomes.  When a new Star Trek movie comes out, Mr. Spock will have to change his greeting to ….”Get married, live long and prosper”!

Until next time…

Dr. Gatis

Is Your Glass Half-Empty or Half-Full?

Does a positive outlook improve your health?  How you perceive your life does matter to your body.  A University of Wisconsin study found that of 30,000 individuals with perceived high stress had a 43 percent increased risk of an early demise – but only if they viewed their stress as negative.

Dr. Jeremy Jamieson, assistant professor of psychology at the University of Rochester,

glass of water with inscription half full, half empty

New York, divided subjects into two groups.  One group was instructed to “reinterpret bodily signals as beneficial” while the other group was not given this information.  Group One, the group prepped beforehand with the instruction, performed better and had less social anxiety.  According to Dr. Jamieson, rethinking how we perceive stress dramatically alters how effectively we cope with “stressful situations and major life transitions”.  Positive thinking skills means that you are better able to handle the everyday stresses of life in a more constructive way.

What are the physical benefits of a positive outlook on life?  Experts at the Mayo Clinic have found that the benefits of maintaining this “life-positive” view translates into lower rates of depression, greater resistance to the common cold and a reduced risk of death from heart disease.

Until next time…

Dr. Gatis

The Key to Health Is in the Mind

Psychoneuroimmunology is the study of the relationship between the mind or psyche, the nervous system and the immune system.  Another way to state this is the relationship between stress the immune system and our health.   When we are “stressed” the body produces “stress-induced” chemicals like cortisol and epinephrine – which are part of our survival mechanism and absolutely necessary.  These chemicals rise in the blood in order to protect us from immediate harm.  The problem arises when these chemicals are chronically elevated due to ongoing stress triggers i.e., modern life.

How can we turn down this stress response, you say?  By increasing its opposite, the

Business People Yoga Relaxation Wellbeing Concept

relaxation response.  It is no mistake that women, in particular, are flocking to the yoga studio.  A review of the literature studying the benefits of yoga found that, compared to no exercise, yoga was linked to a lower rate of obesity, reduced high blood pressure and even tended to reduce high cholesterol.  The Cochrane Collaboration found that yoga can reduce diastolic blood pressure and triglycerides in the blood and increase the HDL (good) cholesterol.

Another easy way to induce the relaxation response is to practice “deep breathing” techniques – which have long been part of meditation.  The researchers at Harvard Medical School found that practicing deep breathing 20 minutes a day for eight weeks increased the expression of genes involved in energy release and increased the protein NF-B – which is part of the body’s response to inflammation, stress and trauma.  The end result is that deep breathing helps to reduce the symptoms of anxiety, lowers heart rate and blood pressure, and improves oxygenation of tissues.

The practice of meditation continues to attract the attention of scientists for its potential stress-relieving effects on the mind and body.  Thailand researchers studied the effects of transcendental meditation (which creates a state of profound relaxation while remaining awake).  Over the course of 18 weeks, study participants felt less anxiety, felt better in social situations at work as well as with their private relationships with family and friends.

Break your stress pattern and take the time to breathe deeply and “smell the roses” – preferably daily.

Take the time to still your mind and body.  Your health depends on it.

Until next time….

Dr. Gatis